Examine This Report on akorn lean syrup
Cure The cure of overdosage with promethazine and phenylephrine is basically symptomatic and supportive. Only in cases of utmost overdosage or individual sensitivity do very important signs such as respiration, pulse, hypertension, temperature, and EKG have to be monitored. Activated charcoal orally or by lavage could be given, or sodium or magnesium sulfate orally being a cathartic.As with all drug, people who are taking other remedies or have underlying healthcare concerns should really speak with their Health care Qualified.
The metabolites as well as their route and rate of excretion haven't been identified. The pharmacologic action of phenylephrine is terminated at least partly by uptake from the drug into tissues.
The main outcome of phenylephrine on the heart is bradycardia; it makes a optimistic inotropic impact on the myocardium in doses higher than These ordinarily applied therapeutically. Not often, the drug may well increase the irritability of the center, triggering arrhythmias. Cardiac output is decreased somewhat. Phenylephrine increases the operate of the heart by escalating peripheral arterial resistance.
Suggest clients never to increase the dose or dosing frequency of promethazine HCl and codeine phosphate oral Remedy because severe adverse functions for instance respiratory melancholy may well come about with overdosage [see Warnings and Safety measures (five.
It’s crucial that you continue to keep this medicine at home temperature and clear of the arrive at of youngsters to prevent any poor consequences. Also, Promethazine Akorn syrup ought to be used meticulously in sure healthcare conditions as it might influence the central nervous program. This syrup is significant for managing respiratory indicators.
WARNING: Hold this and all prescription drugs out with the get to of children. In the event of accidental overdose, seek out Expert aid or Get hold of a poison Handle center promptly.
Phenylephrine is irregularly absorbed from and readily metabolized inside the gastrointestinal tract. Phenylephrine is metabolized from the liver and intestine by monoamine oxidase.
Although antihistamines are identified to provide fetal mortality in rodents, the pharmacological consequences of histamine during the rodent don't parallel All those in guy. There isn't any satisfactory and well-controlled experiments of promethazine in pregnant Gals.
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